Gene
Offers comprehensive data on cuproptosis-related genes (CRGs), including basic information, studies, and expression profiles.
ViewDisease
Compiles diseases linked to cuproptosis through literature mining, highlighting pathological associations.
ViewModulator
Lists modulators that modulate cuproptosis, including inducers or inhibitors for therapeutic exploration.
ViewMechanism
Visualizes key pathways of cuproptosis through diagrams, supported by evidence-based literature.
ViewModSite
Visualizes DNA, RNA, and protein modification sites of CRG to explore regulatory mechanisms.
ViewModAxis
Predicts upstream regulatory cascades of CRGs, offering novel insights for cuproptosis mechanism exploration.
ViewCRG-CoNet
Identifies tumor co-dependency genes associated with CRG and their functional links to cuproptosis.
ViewPath-Net
Covers CRG co-localization with target genes and CRG pathway upstream/downstream gene networks.
ViewData Statistics
Landmark Studies
Copper induces cell death by targeting lipoylated TCA cycle proteins
- First defined cuproptosis mechanism
- Identified DLAT lipoylation as key target
Lactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA
- Revealed lactylation-m6A-FDX1 axis
- Gastric cancer specific regulation